Target : International, multicenter, randomized trial evaluating the impact of using a loading dose of ticagrelor at prehospital stage versus intra-hospital when treating acute myocardial infarction with ST segment elevation, treated by primary angioplasty.

Date of trial : 2011

Number of patients : 1 862

Source of funding : Privé (AstraZeneca)

Participating centers : 112 centers in 13 countries

N°NCT : NCT01347580

STATUS

Design in  Am Heart J. – april 2013

Publication in N Engl J Med. – september 2014

Publication in JACC Cardiovasc Interv. – april 2016

A step further : related sub-studies

  • The hazards of approximations and extrapolations: Insights from the ATLANTIC study
    Publication dans Thromb Haemost. – july 2015
  • The PRIVATE-ATLANTIC study
    Publication dans Thromb Haemost. – august 2016
  • The ATLANTIC ST-segment resolution substudy
    Poster ESC 2016 : pdf
  • How important is the anticoagulant strategy in primary percutaneous coronary intervention ? Insights from the ATLANTIC study
    Presentation ESC 2017 : powerpoint version / pdf version
  • Thrombus aspiration and pre hospital ticagrelor administration in ST-elevation myocardial infarction : findings from the ATLANTIC trial
    Poster ESC 2017 : powerpoint version / pdf version
  • The ATLANTIC-Elderly analysis
    Poster ESC 2017 : powerpoint version / pdf version
  • Clinical impact and predictors of complete ST-segment resolution after primary percutaneous coronary intervention: a subanalysis of the ATLANTIC Trial
    Poster ESC 2017 : powerpoint version / pdf version